Plasma levels of oxidative defense markers—albumin, bilirubin, and uric acid [27,28,29,43,44,45,46,47]—and the activities of antioxidative enzymes, e.g., superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT) [10,28,32,46,48,49,50,51,52], have been compared between MetS-free subjects and those presenting with MetS. This evidence concerns the gene SOD1 and metabolic syndrome.