In a study looking into the molecular mechanism of BBR against insulin resistance, Kong, et al. [64] found that BBR reduced fasting blood glucose (FBG) and fasting serum insulin by increasing insulin receptor (InsR) expression in in vitro and animal studies and by activating the promoter for InsR mRNA and protein production via protein kinase C (PKC) [65]. The gene discussed is INSR; the disease is Insulin resistance.