Recently, ferritin was implied to interact with ferroptosis through selective autophagic degradation of ferritin via nuclear receptor coactivator 4 (NCOA4), namely, ferritinophagy [81,82], which sheds light on the treatment of various diseases, including cancers [83,84], neurodegenerative disorders [85], and immune dysfunction [86,87,88]. Here, NCOA4 is linked to immune system disorder.