CD4 and infection: As shown in Figure 6, by day 4 post-infection, we detected activated virus-specific CD8+ (Figure 6A) and CD4+ T cells in the infected skin, with most gDT-II CD4+ T cells displaying Th2 (GATA3+) (Figure 6B) and Th17 (RORγt+) (Figure 6C) phenotypes.