There is no single laboratory test to diagnose APS, and according to the current state of the art, laboratory diagnosis is performed by measuring the titer of antibodies to cardiolipin (aCL) and β2-Glycoprotein-I (aβ2-GPI), and by searching for the presence of lupus anticoagulant (LA) [1]. The gene discussed is ACLY; the disease is autoimmune polyendocrinopathy.