The mutation of four different genes can give rise to the same ADPKD phenotype: PKD1 and PKD2 (polycystin genes), GANAB (Glucosidase II Alpha Subunit), and DNAJB11 (DnaJ Heat Shock Protein Family (Hsp40) Member B11). This evidence concerns the gene PKD1 and autosomal dominant polycystic kidney disease.