Western blot results showed that, compared to hTERT-HPNE, model genes including KRT7, KRT19, IGF2BP3, and CXCL5, were significantly increased in human pancreatic ductal carcinoma cell lines, PANC-1 and PL45 (Figure 7B). The gene discussed is IGF2BP3; the disease is pancreatic ductal adenocarcinoma.