In humans, these include some autism spectrum disorders and other neurodevelopmental disorders (reviewed in detail in [4]), and more specific disorders, such as horizontal gaze palsy with progressive scoliosis, caused by mutations in the slit ROBO3 receptor (OMIM 607313; [5]), congenital mirror movements that are associated with DCC mutations (OMIM 157600; [6]), congenital fibrosis of the extraocular muscles type 3, and TUBB3 syndromes, related to mutations in TUBB3 (beta-tubulin III, a subunit of microtubules) (OMIM 600638 [7]). Here, TUBB3 is linked to fibrosis.