Similarly, for XRCC4 rs3734071, among the 43 NPC patients, 22 had II, 17 had ID, and 4 had DD genotypes, and there was a trend of reduced mRNA and protein expression levels in patients with the risk genotypes (ID + DD) compared to those with the wild-type II genotype (p = 0.1270 for mRNA comparison, Figure 2D, and p = 0.0929 for protein comparison, Figure 3F). Here, XRCC4 is linked to nasopharyngeal carcinoma.