In the constructed radiation resistance model of PCa cells (LNCaP, DU145, and PC-3), markers of EMT are significantly upregulated, and the markers of CSCs (CD44, CD44v6, CD326, ALDH1, Nanog, and Snail) are also upregulated, suggesting the preliminary correlation between PCSCs and radiosensitivity. The gene discussed is CD44; the disease is posterior cortical atrophy.