It has been described that miR-140-3p plays a role in the proliferation and fibrogenesis of HSCs by regulating PTEN protein, a tumor suppressor protein in the PTEN/AKT pathway that regulates liver fibrosis, indicating that miR-140-3p may be a potential novel molecular target for liver fibrosis [135]. The gene discussed is AKT1; the disease is Hepatic fibrosis.