STAT3 and posterior cortical atrophy: In this review, we focus on specific histopathological markers, particularly CD169 macrophages, neuropilin-1, cofilin-1, interleukin-17, signal transducer and activator of transcription protein 3 (STAT3), LIM domain kinase 1 (LIMK1), prostate-specific membrane antigen (PSMA), Appl1, Sortilin, Syndecan-1, AMACR, CD15, and p63, which in the future may help to establish the prognosis of patients with PCa as well as assist in choosing the most beneficial adjuvant therapy.