The absolute number of Tregs was hardly decreased (CCR4−/−: 100 ± 21 FOXP3+ cells per 1 × 105 tumor cells vs. WT: 151 ± 29 FOXP3+ cells per 1 × 105 tumor cells; n = 9, p = 0.175), with a mean absolute reduction of 51 ± 36, (42.1%). Here, CCR4 is linked to neoplasm.