The number of CD8+ T cells decreased significantly as well (CCR4−/−: 1039 ± 263 CD8+ cells per 1 × 105 tumor cells vs. WT: 2322 ± 307 CD8+ cells per 1 × 105 tumor cells; n = 9, p = 0.0059), with a mean absolute reduction of 1283 ± 405 (59.7%). This evidence concerns the gene CCR4 and neoplasm.