Similar findings were obtained in tumor-bearing mice that had received pharmacological CCR4 inhibition prior to tumor inoculation (tumor implantation n = 20, n = 0 died in <14 days; long-term survivors: n = 9) (median survival 88 days) compared to controls (tumor implantation n = 20; n = 0 died in <14 days; long-term survivors: n = 1) (median survival of 74 days) (p = 0.004) (Figure 2b). Here, CCR4 is linked to neoplasm.