CD59 and paroxysmal nocturnal hemoglobinuria: Furthermore, prostasomes isolated from human seminal plasma, which represent specialized exosomes assembled, stored, and released by the glandular epithelial cells of the prostate [39], have been demonstrated to transfer CD59 to the spermatozoa of human patients suffering from paroxysmal nocturnal hemoglobinuria (PNH) and rabbit erythrocytes [40].