SMARCA1 and non-small cell lung carcinoma: However, the research findings relating the alteration of SWI/SNF complexes to decreasing function of some tumor suppressor genes and increased expression of some oncogenes, as well as weakened DNA damage repair, may provide some clues about the mechanisms of dysregulation of SWI/SNF complexes contributing to the tumorigenesis of NSCLC [41,50,51].