With regard to the immune microenvironment, SWI/SNF complexes are required for the expression of a large number of interferon (IFN)-inducible genes [103], including the induction of CIITA, the master regulator of major histocompatibility complex class II expression, which is essential for the induction of an effective immune response towards the tumor antigen [104]. This evidence concerns the gene SMARCA1 and neoplasm.