One of the most commonly altered pathways driving breast cancer cell progression is the PI3K/AKT/mTOR signaling cascade [29], whereas also the N-terminal c-Jun kinase (JNK) [29] and extracellular-signal-regulated kinase (ERK) [29] in the MAPK pathway have been implicated [10]. The gene discussed is AKT1; the disease is breast carcinoma.