As indicated in Figure 3A,B, the expression of NLRP3, ASC, and cleaved-caspase-1 significantly elevated at 6 h post-stroke (* p < 0.05, ** p < 0.01 vs. Sham group), while IPC treatment could partially reverse it (#p < 0.05 vs. pMCAO group). Here, CASP1 is linked to Stroke.