Additionally, the influence of variations in genes encoding for these enzymes on hyperbilirubinemia has been elucidated, and variations of the UGT1A1 Gly71Arg or UGT1A1 TATA promoter are associated with an increased risk of neonatal hyperbilirubinemia [126]. Here, UGT1A1 is linked to Hyperbilirubinemia.