They demonstrated that miR-125b inhibited proliferation and promoted keratinocyte apoptosis by targeting MMP-2 expression through PI3K/Akt/mTOR pathway [182], and altered expression of miR-21, miR-125b, and miR-203 specifies the role of these miRNAs in OLP [201]. The gene discussed is AKT1; the disease is oral lichen planus.