A study by Wang et al. demonstrated that miR-125b lowered the enhanced phosphorylation of Akt protein and its downstream target, mTOR protein, in LPS-incubated HaCaT cells, highlighting the potential contribution of PI3K/Akt/mTOR signaling pathway aberrations in potential OLP malignancy [182]. The gene discussed is PIK3CD; the disease is oral lichen planus.