Five DO terms were related to kidney diseases, including nephrosis (fold enrichment: 2.76; DEGs: 10), end-stage renal failure (fold enrichment: 2.56; DEGs: 36), insulin resistance (fold enrichment: 1.75; DEGs: 30), diabetes mellitus (fold enrichment: 1.71; DEGs: 82), and type 2 diabetes mellitus (fold enrichment: 1.55; DEGs: 71) (Figure 5). Here, INS is linked to stage 5 chronic kidney disease.