Excess androgens in women with PCOS also place them at higher risk of NAFLD with a recent review highlighting the importance of SHBG, a steroid-binding protein produced in the liver in the regulation of bioavailable androgens in women with a suggestion that levels of SHBG could be used as a biomarker for NAFLD [56]. The gene discussed is SHBG; the disease is metabolic dysfunction-associated steatotic liver disease.