MASP2 and COVID-19: Complement-mediated microvascular injury involving lung and skin, with a marked deposition of C5b-9, C4d, and Mannan-binding lectin serine protease (MASP)-2, suggesting the activation of lectin-based and alternative pathways, was reported among autopsy findings from decedents with severe COVID-19 and acute respiratory distress syndrome (ARDS) [54].