CHI3L1 and diabetes mellitus: One study analyzed these factors in patients with concurrent diabetes and eGFR < 60 mL/min/1.73 m2 by measuring levels of circulating tumor necrosis factor receptors 1 and 2 (TNFR1 and TNFR2), chitinase 3-like 1 (YKL-40) and kidney injury marker 1 (KIM1) in comparison with KFRT risk.