The results of the multivariate logistic regression analysis (Cox and Snell R square 0.220, Nagelkerke R square 0.426, Hosmer–Lemeshow Chi square 1.600, df = 8, p = 0.991) after entering all the variables which had significant crude OR in the univariate analysis (age, severe COVID-19, Brixia score, white blood cell count, lymphocyte count, glucose, urea, creatinine, lactate dehydrogenase, and albumin) have shown that Brixia score was only significantly positively associated with unfavorable outcome (death) (adjusted OR 1.148, 95% CI 1.020–1.292, p = 0.022). This evidence concerns the gene ALB and COVID-19.