With limited reports on the role of TLR4 polymorphisms in cervical cancer, we performed a study to investigate eight selected polymorphisms of the TLR4 gene (rs10759932, rs1927906, rs11536898, rs11536865, rs10983755, rs4986790, rs4986791, rs11536897), whose links to other cancers from other research have been published. Here, TLR4 is linked to cancer.