MKI67 and chronic obstructive pulmonary disease: Previous studies have been focused on the use of T1 mapping in pulmonary diseases, specifically on functional assessment in chronic obstructive pulmonary disease (COPD) [11,12], on the differentiation between benign and malignant lung lesions, based on the different water content [13], and on the identification of lung cancer pathological types [14] and their correlation with Ki-67 expression [15].