SFPQ and adenocarcinoma: By binding to miR-15 family members, repressing LDL receptor-related protein 6 expression, and boosting b-catenin signalling, or by binding to SFPQ (splicing factor proline and glutamine-rich) and dissociating the SFPQ/polypyrimidine tract binding protein 2 dimer, Ji et al. [16] found that metastatic lung adenocarcinoma transcript 1 could regulate the transcription and translation of RUNX2.