TNF and atherosclerosis: A KEGG analysis indicated that the above genes have a role in cytokine–cytokine receptor interactions, natural-killer-cell-mediated cytotoxicity, the B cell receptor signaling pathway, the chemokine signaling pathway, lipid and atherosclerosis, the TNF signaling pathway, osteoclast differentiation, and the Toll-like receptor signaling pathway (Figure 5B).