Functional analysis based on the Z-score and −log(p-value) indicated activation of the kinetochore metaphase signaling pathway (2.71, 7.35), PTEN pathway (2.64, 2.31), HOTAIR regulatory pathway (2.12, 2.71), and WNT/β-catenin signaling pathway (2.45, 1.47), and suppression of the senescence pathway (−3.16, 3.02), phagosome formation (−3.15, 2.09), FAK signaling (−3.128, 1.74), oxytocin signaling pathway (−3.05, 3.8), and breast cancer regulation by Stathmin1 (−3.0, 2.06) (Figure 3). The gene discussed is HOTAIR; the disease is breast cancer.