NOS3 and hypertensive disorder: PD-related genes also appeared to play a role in toxicity risk—SNPs in vascular endothelial growth factor receptor 2 (VEGFR2), FMS-like tyrosine kinase 3 (FLT3), vascular endothelial growth factor A (VEGF-A), and endothelial nitric oxide synthase (eNOS) were associated with sunitinib-related toxicities, particularly hypertension.