Therefore, as a model system, we chose two human CD4+ cutaneous T-cell lymphoma cell lines that harbored mutations in TP53 (http://cellosaurus.org (accessed on 12 June 2023)) [35], which is frequently seen in cutaneous T-cell lymphomas [21], and both were RHOA-WT (according to depmap: Cancer Dependency Map, Broad Institute, 415 Main Street, Cambridge, MA 02142, USA and own Sanger sequencing of codon 17). Here, RHOA is linked to primary cutaneous T-cell non-Hodgkin lymphoma.