MICALL2 is more expressed in ccRCC tissues and cell lines compared to healthy tissue and normal renal tubular epithelial cell lines and it was shown to have a predictive function in ccRCC carcinogenesis; in fact, MICALL2 overexpression led to enhanced cell proliferation, migration and invasion, while its knockdown had an opposite effect. Here, MICALL2 is linked to nonpapillary renal cell carcinoma.