Collectively, the evidence shows that nine genes (CST6, TRIM29, CSTA, KRT15, KLK7, MME, CXCL13, FA2H, and HRNR) negatively impact BC, while five genes (FABP4, AQP3, KRT16, SERPINB3, and ATP6V1C2) are likely to facilitate BC (Table 1). The gene discussed is CST6; the disease is breast cancer.