Furthermore, a number of interferon (IFN) response genes (BST2, CD74, HLA-DMA, HLA-DPB1, HLA-DQB1, HLA-DRA, HLA-DRB1, and IRF8) were upregulated in C10 compared to the other clusters, whereas genes associated with tumor suppression and apoptosis (TFF1 and TFF2) were downregulated (Figure 5D). The gene discussed is HLA-DQB1; the disease is neoplasm.