In SHH medulloblastoma, the downregulation of miR-466f-3p, together with the concordant upregulation of VEGFa and Neuropilin 2, encouraged cell proliferation and the self-renewal ability of CSCs through the EMT process, which sustained the mesenchymal phenotype of SHH medulloblastoma CSCs [131]. Here, NRP2 is linked to medulloblastoma.