However, it has been widely accepted that germinoma is a prototype of all GCTs, by CSC markers of Oct4, Nanog, SOX17 (germinoma), SOX2 (infantile GCTs), and differentiation markers of PLAP and KIT (germinoma differentiation markers from ES cells, rare in intracranial none germinoma GCTs (NGGCTs)) [50]. Here, POU5F1 is linked to germinoma.