TP53 and posterior cortical atrophy: Notably, miRNAs are involved in the regulation of multiple key signaling pathways in PCa progression, such as androgen receptor (AR) signaling [26,27], PTEN/PI3K/AKT signaling [28], p53 signaling [29], Wnt/β-catenin signaling [30], and autophagy [31] pathways.