Although this xenograft assay does not account for all steps required for a tumor cell to achieve metastatic colonization (extravasation, survival in blood, seeding of new site, proliferation in new site), and they measured colonization of lungs using a lung cancer cell line (same tissue), it raises the possibility that HOTAIR may be involved in the seeding and survival of cancer cells. The gene discussed is HOTAIR; the disease is neoplasm.