It has been previously reported that PD-L1-positive subcutaneous LOX melanoma tumours are strongly PET-avid for both 18F-AlF-NOTA-ZPD-L1 and 68Ga-NOTA-ZPD-L1 affibody-based radioconjugates, whereas PD-L1-negative SUDHL6 lymphoma tumours show minimal uptake [12,35]. The gene discussed is CD274; the disease is melanoma.