This article summarizes existing knowledge about the roles of CXCL ELR-positive chemokines CXCL1, CXCL2, CXCL3, CXCL5, CXCL6, CXCL7, and CXCL8 as peripheral blood and tissue markers in the diagnosis and prognosis of women with breast cancer. The gene discussed is CXCL3; the disease is breast cancer.