The inhibition of IRAK1 by gene silencing and small molecule inhibitors was found to induce apoptosis and a decrease in cell viability in melanoma, gastric cancer, lymphoblastic leukemia, pancreatic cancer, Kaposi carcinoma, cervical cancer, and hepatocellular carcinoma [207,208,209,210,211]. Here, IRAK1 is linked to acute lymphoblastic leukemia.