IRAK1 and posterior cortical atrophy: Hence, the overarching goal of our research group is to investigate and elucidate the oncogenic role of the less-studied midstream regulatory and adaptor proteins in the inflammatory cascade, particularly the role of interleukin-1 receptor-associated kinases (IRAKs) in prostate tumor progression, as well as to gain insight into their diagnostic, prognostic, and therapeutic potentials in chronic inflammation-driven PCa [112,113,114].