Several studies investigated the association between mpMRI findings (e.g., tumor visibility and PI-RADS) with transcriptomics-based scores and molecular biomarkers from biopsied cancer tissue, including Prolaris, Decipher, the genomic prostate score, and expression of phosphatase and tensin homolog (PTEN) [21,29,30,31,32]. This evidence concerns the gene PTEN and cancer.