MFF and liver cancer: In liver cancer, the complex formed by T-box transcription factor 19 (TBX19) and PRMT1 induces MFF expression by increasing histone H4R3me2a/H3K9ac levels; then, MFF promotes mitochondrial fission, increases the expression level of OCT4, enhances the formation of tumorspheres and enriches the side populations (SPs) [91] (Fig. 3B).