In pancreatic cancer, lncRNA SLC7A11-AS1 promoted stemness potential by scavenging ROS, which functioned by interacting with β-TRCP1 and then blocking nuclear factor erythroid-2-related factor 2 (NRF2) degradation [110] (Fig. 5A). This evidence concerns the gene NFE2L2 and familial pancreatic carcinoma.