This model, which was based on 13 ARGs, including GNAI3, FKBP1A, BIRC5, SH3GLB1, HIF1A, RHEB, EIF2S1 RAB1A, ATIC, NPC1, PRKCD, ATG4B, and CLN3, can predict the prognosis of HCC. The gene discussed is NPC1; the disease is hepatocellular carcinoma.