In this study, by analyzing the clinical and transcriptome data of HCC in the Asian population downloaded from the TCGA database and human ARGs, 13 significant prognosis-related ARGs, namely, GNAI3, FKBP1A, BIRC5, SH3GLB1, HIF1A, RHEB, EIF2S1 RAB1A, ATIC, NPC1, PRKCD, ATG4B, and CLN3, were screened via multifactorial Cox regression analysis. The gene discussed is PRKCD; the disease is hepatocellular carcinoma.