Sixteen predictive factors were identified that affect the live birth before and after the first cycle of IVF/ICSI including maternal age, AMH, basal E2, basal PRL, infertility duration, the number of pregnancies, the number of left sinus follicles, serum HCG level, EMT on HCG day, LH level on HCG day, E2 level on HCG day, Gn, method of fertilizations, types of transferred embryos, stimulation protocols, and endometrial preparation protocol. The gene discussed is PLOD1; the disease is Infertility.