YTHDF2 and cancer: Other examples supporting the role of the METTL3/YTHDF2 m6A axis in metastasis include the decay of targets with tumor suppressor functions, as YPEL5 (associated with decrease of CCNB1 and PCNA expression) in CRC [237], USP4 in prostate cancer [238], DUSP5 in gallbladder cancer [239], and IFFO1 in different types of cancer [240].