Moreover, as previously commented for YTHDF1 [247], the same team found that insufficient radiofrequency ablation of HCC also results in a significant upregulation of METTL1/WDR4 and m7G levels in tRNAs that could promote metastasis by enhancing the translation of SLUG/SNAIL EMT regulators [298]. This evidence concerns the gene YTHDF1 and hepatocellular carcinoma.