In recent studies, it has been found that the interaction of cell migration-inducing protein (CEMIP) with inositol 1/4 in prostate cancer cells activates the nuclear factor erythroid 2-related factor 2 (NRF2) and promotes the transcription of solute Carrier Family 7, Member 11 (SLC7A11), (a glutamate/cysteine antiporter solute family 7 member). Here, NFE2L2 is linked to Familial prostate cancer.