ALKBH5 and lung carcinoma: Subsequent reports showed that ALKBH5 was upregulated and could facilitate cancer cell stemness and self-renewal, tumorigenesis, and progression by removing m6A from the mRNA of target genes in glioblastoma, acute myeloid leukemia, breast cancer, gastric cancer, and lung cancer; moreover, other studies have shown that ALKBH5 inhibits tumorigenesis and metastasis in lung cancer and pancreatic cancer14,16–19.