Caution is advised in patients who are already immunosuppressed as a consequence of other therapies, with an absolute neutrophil count of less than 500 cells/μL or a platelet count of less than 50 × 103 cells/μL.36 For example, one expected interaction is between corticosteroids and IL-6 inhibitors, as these are both indicated in severely ill patients with COVID-19 requiring oxygen or ventilatory support.23 This is a PD DDI that would likely be flagged in databases. The gene discussed is IL6; the disease is COVID-19.