Moreover, in the serum of patients with glioblastoma (the most typical parenchymal brain tumor), it has been reported that there is a significant overexpression of IL-6, IL-1β, TNF-α, IL-10, VEGF, FGF-2, IL-8, IL-2, and GM-CSF [19]. The gene discussed is VEGFA; the disease is glioblastoma.