IMPs also seem to be correlated with EMT (and thus also of the presence of CSC): You et al. [163] demonstrated that epithelial-mesenchymal transition in colorectal carcinoma cells was mediated by DEK/IMP3; in fact, once this network was silenced, the level of E-cadherin was enhanced and the expression of vimentin and MMP-9 were apparently downregulated, influencing the invasion of colorectal carcinoma cells negatively. The gene discussed is IMP3; the disease is colorectal carcinoma.